Log in

Efficient development of clinical-grade prediction models of cancer treatment outcomes

1 May 2019 10:28 AM | Marie-Louise Rankin (Administrator)

South Australia Branch Meeting, April 2019

The speaker for the April 2019 meeting of the SA Branch was Professor Michael Sorich. He is a clinical epidemiologist, biostatistician, and pharmacist from Flinders University with a primary research interest in the use of biological, chemical, and clinical markers to guide decisions regarding the most appropriate use of medicines (precision medicine). His current research primarily focuses on evaluation and evidence development with respect to precision medicine approaches informing the use of cancer medicines. This includes analysis of pooled clinical trial data, and evaluation of patient data from routine clinical care.

Michael’s talk “Efficient development of clinical-grade prediction models of cancer treatment outcomes” is a piece of his current research works funded by a Beat Cancer project grant. At the beginning of his talk, Michael described the precision medicine - an approach to improving the practice of medicine based on understanding the individual characteristics that are associated with, and potentially causative of, drug therapeutic and adverse effects. Using a number of example studies, Michael highlighted the significant advances achieved in precision medicine over the last decade that enable understanding of biological differences between individuals. There are many potential benefits of precision medicine including minimizing risk of drug toxicity, increasing benefit from drugs used, contributing to the sustainability of the healthcare system and facilitating drug discovery and development programs. In particular, Michael highlighted the treatment benefit in advanced cancer by showing a classical example of anti-EGFR therapy for advanced colorectal cancer.

Clinical prediction models were mainly discussed in his talk - an option for providing more personalised estimates of prognosis, harms and potentially treatment benefit. Michael’s talk mainly covered the barriers that exist to developing prediction models that may be used to guide clinical practice and decisions, and emerging data platforms that may help overcome many of these issues. The detail of his talk and particularly prediction models of cancer treatment outcomes can be found by contacting

A dinner was held right after the meeting at Jasmin Indian Restaurant, 31 Hindmarsh Square, Adelaide.

By Shahid Ullah


  • 25 Sep 2019 9:28 AM | Benjamin Seyler
    Cancer is the harmful decease and it can damage the health of patients quickly. According to my research some clients are not satisfied from assignment writing services because they didn’t get writing services according to their requirements. Sometime this site does not work properly and people are facing issues while placing orders there.Now people are using new techniques to get rid from cancer and they can take best medicine to get relief from cancer.
    Link  •  Reply
    • 22 Oct 2019 4:32 PM | Anonymous
      No doubt there cancer vaccine save the lives of many people but many work yet to done in this field. Your efforts are appreciative for making the organization able to diagnose and predict well the patients. As a medical student, I find it impressive in the preparation of my assignment with website's help that all means to have good grades as well as sound knowledge of research.
      Link  •  Reply
Powered by Wild Apricot Membership Software